Symbol
Name
ID

Spns2
SPNS lysolipid transporter 2, sphingosine-1-phosphate
MGI:2384936

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

decreased thymocyte number

decreased immature B cell number

decreased transitional stage T1 B cell number

increased mean corpuscular hemoglobin

increased granulocyte number

abnormal leukocyte cell number

abnormal mature B cell number

decreased mature B cell number

decreased B-1 B cell number

decreased follicular B cell number

decreased B cell number

increased NK cell number

decreased CD4-positive, alpha-beta T cell number

increased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased NK T cell number

decreased T cell number

decreased single-positive T cell number

increased single-positive T cell number

decreased lymphocyte cell number

decreased monocyte cell number

increased monocyte cell number

decreased leukocyte cell number

abnormal effector T cell morphology

abnormal B cell physiology

decreased IgG1 level

decreased IgG level

abnormal T cell physiology

Availability

Mouse Genotype

Spns2^tm1.2Nmoc/Spns2^tm1.2Nmoc

Spns2^{tm1a(KOMP)Wtsi}/Spns2^{tm1a(KOMP)Wtsi}

Spns2^{tm1b(KOMP)Wtsi}/Spns2^{tm1b(KOMP)Wtsi}

Spns2^tm1Tni/Spns2^tm1Tni

Spns2^tm1.1Nmoc/Spns2^tm1.1Nmoc
Tg(Tek-cre)1Ywa/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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